Turning bioscience breakthroughs into impact — on St. Louis and the world.
BioGenerator, the startup arm of BioSTL, creates, builds and invests in St.Louis companies that are solving global challenges in human health and agriculture.
It takes more than a great idea to grow a company.
BioGenerator provides founders with every advantage to succeed.
BioGenerator
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142
All-Time Portfolio Companies
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$52.1M
invested
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$2.9B
VC Raised
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137
BioGenerator Grant-Supported Concepts
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215
Lab Clients
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$4.5M
Total BioGenerator Grants
Solis Agrosciences
Advancing Agtech Innovation Through Research Excellence
Founded in 2021, Solis Agrosciences provides high-quality agricultural research services, including plant transformation, gene editing, phenotyping, and sequencing. BioGenerator helped conceive Solis’ business plan, recruited founding leadership, and provided initial funding and lab space, laying the groundwork for the company’s rapid growth and strategic expansion. Solis now serves a growing client base of startups and large companies.
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Geneoscopy
Transforming Gastrointestinal Health Through Noninvasive Diagnostics
Founded in St. Louis, Geneoscopy is advancing gastrointestinal health with its FDA-approved ColoSense® test, which analyzes RNA biomarkers from stool samples to detect colorectal cancer early and accurately. BioGenerator provided early lab space, funding, and strategic guidance that helped launch the company’s growth and attract major investors.
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Wugen
Pioneering Off-the-Shelf CAR-T Therapies for T-Cell Leukemia
Wugen is developing off-the-shelf CAR-T therapies for T-cell leukemia and other cancers. With early investment and lab space from BioGenerator, Wugen built its team, scaled R&D, and advanced its lead therapy, WU-CART-007, now showing promising clinical results and is advancing through pivotal trials—positioning Wugen at the forefront of next-generation cell therapy innovation.
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SweetSpot
Transforming Diabetes Care Through Connected Technology and Clinical Support
Co-founded through BioGenerator’s Entrepreneur-in-Residence program, SweetSpot integrates real-time glucose data, insulin insights, and clinical support into one connected platform for diabetes care. With BioGenerator’s early capital and leadership recruitment, SweetSpot now partners with endocrinology practices nationwide to deliver personalized, continuous care.
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Pairidex
BioGenerator-supported Pairidex Advances Precision Monitoring for Blood Cancer Patients
Pairidex is developing a highly sensitive, personalized platform to monitor blood cancers using droplet digital PCR technology. By detecting cancer at extremely low levels, its approach enables clinicians to track disease progression and treatment response with greater accuracy. BioGenerator Ventures co-founded Pairidex and continues to support its growth through early funding, lab infrastructure, and hands-on operational leadership.
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Agragene
BioGenerator-supported Agragene Advances Sustainable Crop Protection with Genetic Pest Control Technology
Agragene is developing a novel, environmentally sustainable approach to pest management using gene editing to suppress harmful insect populations. Its technology produces sterile male pests that naturally reduce reproduction, with its lead product targeting a major threat to berry crops. BioGenerator Ventures supported Agragene’s relocation, early growth, and continued scale through investment, leadership guidance, and ecosystem connections.
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